BTS Skills Gap Initiative: 2025 training modules

Event Date: March 10th 2025 - January 1st 2026

Non-Member Cost: £250 per module

Member Cost: £250 per module

Website: https://execbs.eventsair.com/bts-skills-gap-initiative2025-training-modules/skills-gap-initiative-module-1/Site/Register


Following the success of the first training module ‘An Introduction to the principles of regulatory toxicology: present and future’ which attracted more than 150 registrations, the BTS Skills Gap Initiative (supported by the Advisory Board and Steering Committee) is pleased to announce the following training modules planned for 2025.

>REGISTER HERE<

Core Module 1 (repeat) Introduction to the principles of regulatory toxicology: present and future
This introductory module takes a critical approach to the conduct and interpretation of toxicity studies in light of risk assessment, emphasising the need to employ a flexible approach in order to maximise understanding of toxicity and relevance to human risk assessment across different industry sectors and regulatory principles.

The module will be delivered as six 2-hour webinars in June and July 2025, with an in‑person workshop to be held in London in September 2025.  Delegates will have access to recordings of all webinars.

Webinar 1          INTRODUCTION TO REGULATORY TOXICOLOGY
T
hursday 26th June 2025, 10:00-12:00

Overview of regulatory toxicology, its aims and purpose – Charlotte Thorpe, HSE

Overview of hazard and risk assessment, including classification and labelling – Dr Susy Brescia, HSE

Summary of the current situation and potential future changes in regard to animal testing and NAMs – Dr Camilla Alexander-White, RSC

Q&A session – All speakers

Webinar 2          ACUTE TOXICITY, IRRITATION & SENSITISATION
Friday 27th June 2025: 10:00-12:00

Acute oral and dermal toxicity studies – Hayley Parker, Labcorp

Acute inhalation toxicity – Dr Jo Kilgour, Mereside Toxicology Consulting

Irritation & sensitisation studies – Claire Elliott, Penman Consulting

Q&A session – All speakers

Webinar 3           GENOTOXICITY
Tuesday 1st July 2025 10:00-12:00

Genotoxicity studies: introduction, general principles – Dr Katherine Chapman, Swansea University

The use of (Q)SAR as a predictor of genotoxicity – Dr Alex Cayley, Lhasa Limited

Mechanisms of genotoxicity, implications for risk assessment – Dr Paul Fowler, FStox

Q&A session – All speakers

Webinar 4           REPEATED DOSE TOXICITY & CARCINOGENICITY
Monday 7th July 2025, 10:00-12:00

Repeated dose toxicity: general principles – Dr Meera Cush, Ramboll

Carcinogenicity studies – Helen-Marie Dunmore, Certara

Pathological findings – Dr Cheryl Scudamore, RSA

Q&A session – All speakers

Webinar 5           DART & Endocrine Disruptors
Thursday 10th July 2025, 10:00-12:00

Introduction to developmental and reproductive toxicology studies – Dr Hollie Blunt, Sequani

Overview of endocrine disruption – Dr Jason Manton (Toxiqua)

Use (and potential future use) of NAMs in repeated dose toxicity and DART – Dr Matthew Dent (Unilever)

Q&A session – All speakers

Webinar 6           ADME / TOXICOKINETICS
Tuesday 15th July 2025, 10:00-12:00

Overview of ADME / toxicokinetics – Alex Gledhill, ERM

Overview of in vitro methods of metabolism & absorption – Katherine Knowles, Syngenta

Introduction to PBPK modelling – Dr Ciarán Fisher, GSK

Q&A session – All speakers

Workshop           REGULATORY TOXICOLOGY: CASE STUDIES
Early September 2025, Central London location (tbc)

Delegates will be provided with a number of regulatory toxicology case studies prior to the Workshop.  Case studies will be discussed by delegates in small groups in the Workshop, with guidance from experienced regulatory toxicologists, and in a plenary session.

Core Module 2 PBPK Modelling
Webinars: March/April 2025

  • Introduction to PBPK modelling
  • Hands-on training session
  • Population variability, transporters, in vitro biokinetics
  • Hands-on training session
  • Agrochemical, pharmaceutical and consumer products industry case studies
  • Regulatory perspectives; open-source and commercial tools

The BTS Skills Gap Initiative Advisory Board and Steering Committee thank Certara for supporting this module.

Core Module 3 Genotoxicity
Webinars including interactive elements (w/c 14th July 2025)

  • Introduction to genotoxicity; modes of action, in vitro methods and new developments
  • In vivo methods and the 3Rs
  • Quantitative and qualitative assessment of genotoxicity data
  • New Approach Methodologies in genotoxicity, including in silico and organ on a chip models
  • The regulatory perspective (1); case studies covering CLP classification, agrochemicals and REACH
  • The regulatory perspective (2); case studies pharmaceuticals and cosmetics
Core Module 4 (Q)SAR
Webinars

  • What are (Q)SAR models and how do they work? 25th September 2025
  • Considerations when building useful (Q)SAR models: 29th October 2025
  • Applying (Q)SAR models in decision-making workflows: 19th November 2025
  • What next for (Q)SAR modelling? 12th December 2025

In-person workshop: 21st January, 2026 (Leeds)

Core Module 5 Developmental & Reproductive Toxicology
Webinars:  November / December 2025

  • Introduction to DART and its regulatory assessment
  • DART testing for pharmaceuticals
  • DART testing for chemicals
  • Practicalities of DART assessment
  • Regulatory requirements for chemicals and pharmaceuticals
  • The current and future application of NAMs in DART assessment
  • Paediatrics
Supplementary Module 1 Ecotoxicology & Environmental Toxicology
Webinars:

  • General principles and regulatory context, ecotoxicology studies (aquatic and sediment organisms): w/c 21st April 2025
  • Ecotoxicology studies (avian, wild mammals, non-target arthropods, soil organisms, pollinators, endocrine disruption: w/c 28th April 2025
  • Use of NAMs in ecotoxicology: w/c 5th May 2025
  • Overview of environmental fate and behaviour studies, environmental fate assessment: w/c 19th May 2025
  • Regulatory perspective: environmental risk assessment of pesticides, REACH chemicals, pharmaceuticals: w/c 2nd June 2025

In-person Workshop: Next Generation Risk Environmental Risk Assessment:  w/c 9th June 2025 (Central London)

Supplementary Module 2 Regulatory Risk Assessment
Webinars:  May/June 2025

  • Regulatory risk assessment (human and veterinary pharmaceuticals)
  • Regulatory risk assessment (REACH)
  • Regulatory risk assessment (cosmetics)
  • Virtual Workshop: comparison of risk assessment approaches under different regulatory regimes

The 2025 training modules will be presented by experts from industry, academia and regulatory authorities, and are intended provide more in-depth training in areas of interest.  The first training module will also be repeated this year.

Registration for each module is open, with a registration cost of £250 per module.  A certificate of attendance will be provided on completion of a module.

Please note that timings and content detail may be subject to change.   Modules have a registration limit, and also require a minimum number of participants to go ahead.

>REGISTER HERE<