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Opportunities for the application of the 3Rs in toxicology studies

It is accepted good practice that scientists who use animals should apply the 3Rs principles  – Replacement, Reduction and Refinement – to limit the impact of research on animals. In the UK, the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) plays a major role in coordinating and promoting activities to minimise the use of animals in research and support the development of new 3Rs approaches….