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Developmental and Reproductive Toxicology

This postgraduate course introduces the field of developmental and reproductive toxicology (DART) from the viewpoint of a variety of contributing disciplines. Starting from basic reproductive, developmental, endocrine and toxicological concepts, it covers subjects from experimental research to clinical studies and epidemiology. Specific topics include advice on drugs use in pregnancy, the teratology of antiepileptic drugs, folic acid deficiency and neural tube defects, and the classical and still topical DES and Thalidomide cases. Special attention is given to the interpretation of animal reproductive toxicity studies which form the basis for human risk assessment of chemicals.

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