General Toxicology
The aim of the course is twofold. Firstly, it offers participants who seek vocational training but lack formal undergraduate training in toxicology the opportunity to obtain extensive, basic theoretical knowledge and insights in this field. Secondly, this module can serve as a refresher course for PhD students and others who intend to take some of the other PET programme modules. The course consists of a directed self study of most of the contents of the general toxicology textbook Casarett and Doull’s Essentials of Toxicology. C.D. Klaassen and J.B. Watkins III, Eds. 4th Edition, 2021. McGraw-Hill, New York. ISBN-13: 978-1260452297. Candidates will need this book to study the subject matter of this course and it has to be purchased by themselves. Currently the course does not contain e-lectures. Instructions and extensive self-tests are offered via an online learning environment.
Subject matter:
UNIT 1 – General principles of toxicology
Chapter 1 – History and Scope of Toxicology
Chapter 2 – Principles of Toxicology
Chapter 3 – Mechanisms of Toxicity
Chapter 4 – Risk Assessment
UNIT 2 – Disposition of toxicants
Chapter 5 – Absorption, Distribution, and Excretion of Toxicants
Chapter 6 – Biotransformation of Xenobiotics
Chapter 7 – Toxicokinetics
UNIT 3 – Non-organ directed toxicity
Chapter 8 – Chemical Carcinogenesis
Chapter 9 – Genetic Toxicology
Chapter 10 – Developmental Toxicology
UNIT 4 – Target organ toxicity
Chapter 11 – Toxic Responses of the Blood
Chapter 12 – Toxic Responses of the Immune System
Chapter 13 – Toxic Responses of the Liver
Chapter 14 – Toxic Responses of the Kidney
Chapter 15 – Toxic Responses of the Respiratory System
Chapter 16 – Toxic Responses of the Nervous System
Chapter 18 – Toxic Responses of the Heart and Vascular System
Chapter 19 – Toxic Responses of the Skin
Chapter 20 – Toxic Responses of the Reproductive System
Chapter 21 – Toxic Responses of the Endocrine System
UNIT 5 – Toxic agents
Chapter 22 – Toxic Effects of Pesticides
Chapter 23 – Toxic Effects of Metals
Chapter 24 – Toxic Effects of Solvents and Vapours
Chapter 26 – Toxic Effects of Plants and Animals
Course Type: Commercial Courses
Learning Type: Online
Start Months: e-learning- can be started anytime
Course Duration: Full Time
Full Time Hours: Not specified
Qualifications Required: No formal qualification
Cost: €200 internal PhD student, €500 external PhD student, €1250 other
Contact details of organiser: Postgraduate Education in Toxicology (PET)
