Dr Fiona Sewell

Dr Fiona Sewell is a Head of n Toxicology at the NC3Rs, where she specialises in animal use in the pharmaceutical and chemical industries.  She convenes expert working groups which take an evidence-based approach to explore and support new opportunities to minimise and refine the use of a variety of species including non-human primates, dogs and rodents.  Her publications include recommendations on the incorporation of recovery animals to support first-in-human clinical trials, an evidence-based approach to define body weight loss limits to refine short-term toxicity studies and evidence to support the use of ‘evident toxicity’ as a refined endpoint in acute inhalation studies.  Fiona joined the NC3Rs in 2012 following a Postdoctoral Research Associate position at Imperial College London.  She has a PhD in translational research from the Cancer Research Clinical Centre at the University of Leeds, and an MSc in Applied Toxicology from the University of Surrey.